Global Blood Plasma Products Market Size
The Global Blood Plasma Products Market reached USD 16.8 billion in 2016 and should reach USD 23.0 billion in 2021, growing at a compound annual growth rate (CAGR) of 6.6% from 2016 through 2021.
Global Blood Plasma Products Market Overview:
Plasma is referred as a blood component constituting of water along with other components like glucose, immunoglobulin, electrolytes, hormones, electrolytes, and clotting factors. It plays a vital role in maintaining the electrolyte and osmotic balance, preventing infections and blood disorders in the body. Plasma derivatives are the concentrates of specific proteins, which need pooling of plasma from great number of donors. For example, to treat an immune-deficient patient for one year they require more than hundred plasma donations to produce enough immunoglobulin. Hence, they are obtained by the process of fractionation where protein concentrates are separated and then clinically used.
Drivers and Restraints:
The development of the global blood plasma derivatives market is majorly driven by rise in prevalence of life-threatening disorders, particularly hemophilia. Other factors boosting the market development include increase in adoption of blood plasma derivatives products, upsurge in geriatric population across the world, and rise in awareness about blood & plasma donation. However, factors such as high cost of plasma derivative-based therapy and post-operative risks associated with plasma replacement therapy hamper the market development. On the other hand, the development of enhanced methods for preservation of plasma derivatives along with advanced procedures for fractionation and high potential in untapped markets in the developing economies are projected to provide lucrative growth opportunities for the market.
Report Scope:
This research report presents an in-depth analysis of the global blood plasma market by application, product category, mode of delivery, end user and geographic market. The report includes key blood plasma products used in various therapeutic treatments as well as an examination of the supply chain from research to manufacturing. The report also features an in-depth analysis of key companies operating in the global blood plasma market and patents that highlight past, current and projected global technology trends.
The blood plasma market is primarily segmented into five major blood plasma components: immunoglobulin, albumin, hyperimmune, coagulation factors, and other plasma fractionation products. Immunoglobulins are further segmented into intravenous immunoglobulins, subcutaneous immunoglobulins and normal immunoglobulins such as immunoglobulin A (IgA), immunoglobin D (IgD), immunoglobin E (IgE), immunoglobin G (IgG), and immunoglobin M (IgM). The global blood plasma market is further segmented by the application which helps in understanding the potency of blood plasma products in several therapeutic treatments. Products based on these applications are explored in detail and their influence on R&D is examined. The market is segmented by geography into North America, Europe, Asia-Pacific, and RoW. Companies profiled in this report include Grifols S. A., Octopharma AG, Biotest AG, Shire, CSL Ltd., Kedrion S.p.A., China Biologic Products, Sanquin, and others.
Report Includes:
- An overview of the global markets for blood plasma products.
- Analyses of global market trends, with data from 2015 and 2016, and projections of compound annual growth rates (CAGRs) through 2021.
- Analysis of the market by product, application, mode of delivery and by end user.
- Coverage of segmentation of blood plasma products, including immunoglobulin, albumin, protease inhibitors, coagulation factor concentrates and other plasma fractionation products.
- In-depth analysis of the key strategies adopted by industry players, such as acquisition and geographical expansion.
- A look at major factors driving the growth of the global blood plasma products markets, including an organized network of donor centers and rising disease awareness and education.
- Profiles of major players in the industry.
Detailed Segmentation of Global Blood Plasma Products Market:
Global Blood Plasma Products Market Analysis – By Product Type:
- Immunoglobulins
- Intravenous Immunoglobulin
- Subcutaneous Immunoglobulin
- Albumin
- Hyperimmunes
- Coagulation Factor Concentrates
- Other Plasma Fractionation Products
- Protease Inhibitors
- Others
Global Blood Plasma Products Market Analysis – By End User:
- Hospitals and Clinics
- Research Laboratories
- Academic Institutions
Global Blood Plasma Products Market Analysis – By Application:
- Immunology
- Oncology
- Pulmonology
- Rheumatology
- Transplant
- Neurology
- Hematology
- Others
Global Blood Plasma Products Market Analysis – By End User:
- Infusion Solutions
- Gels
- Sprays
- Biomedical Sealants
Global Blood Plasma Products Market Analysis – By Region:
- North America
- Europe
- China
- Japan
- Middle East & Africa
- India
- South America
- Others
Key Players in Global Blood Plasma Products Market:
- Fusion Health Care Pvt. Ltd.
- SK Plasma Co.
- Biotest AG
- Green Cross Corporation Ltd. S.A.
- Octapharma AG
- CSL Limited
- LFB S.A.
- Baxter International Inc
- Shire Plc
Table of Contents
Chapter 1: Introduction .. 1
Study Goals and Objectives ... 1
Reasons for Doing This Study .. 1
Scope of Report .. 1
Information Sources and Methodology .. 2
Intended Audience .. 2
Geographic Breakdown .. 3
Analyst's Credentials .. 5
Related BCC Research Reports .. 5
Chapter 2: Summary and Highlights .. 7
Chapter 3: Market and Technology Background .. 11
Blood Donation .. 11
Components of Blood Plasma .. 12
Functions of Blood Plasma .. 12
Collection and Extraction of Blood Plasma .. 14
Government Funding of Blood Donation Facilities .. 15
FDA, International Regulatory Agencies and Medical Associations .. 15
Clinical Guidelines .. 16
Technology Trends .. 16
Market Dynamics .. 17
Drivers .. 17
Restraints .. 19
Opportunities .. 20
Chapter 4: Market Breakdown by Product Type .. 22
Immunoglobulins .. 23
Intravenous Immunoglobulin .. 24
Subcutaneous Immunoglobulin .. 25
Others .. 27
Albumin .. 28
Hyperimmunes .. 29
Coagulation Factor Concentrates .. 30
Other Plasma Fractionation Products .. 31
Protease Inhibitors .. 31
Chapter 5: Market Breakdown by End User .. 34
Hospitals and Clinics .. 35
Research Laboratories .. 35
Academic Institutions .. 36
Chapter 6: Market Breakdown by Application .. 40
Immunology .. 41
Oncology .. 42
Pulmonology .. 44
Rheumatology .. 45
Transplant .. 47
Neurology .. 48
Hematology .. 51
Others .. 52
Chapter 7: Market Breakdown by Mode of Delivery .. 55
Infusion Solutions .. 55
Gels .. 56
Sprays .. 57
Biomedical Sealants .. 58
Chapter 8: Market Breakdown by Region .. 61
North America .. 61
U.S. .. 65
Canada .. 66
Mexico .. 67
Europe .. 67
U.K. .. 72
Germany .. 73
France .. 74
Rest of Europe .. 75
Asia-Pacific .. 75
China .. 78
Japan .. 80
Australia .. 80
India .. 81
Rest of Asia-Pacific .. 82
RoW .. 83
Latin America .. 85
Africa .. 86
Middle East .. 87
Chapter 9: Patent Review of Blood Plasma Products .. 90
Patent Analysis .. 90
Patent Review by Year .. 90
Patent Review by Region .. 91
Patent Review by Assignee .. 93
Chapter 10: Analysis of Market Opportunities .. 97
Chapter 11: Company Profiles .. 104
Appendix .. 125
North American Patents .. 125
European Patents .. 126
Asia-Pacific Patents .. 128
RoW Patents .. 132
About BCC Research ..136
About BCC Research .. 137
BCC Membership .. 137
BCC Custom Research .. 137
List of Tables
Summary Table: Global Market for Blood Plasma, by Region, Through 2021 ($ Millions) .. 8
Table 1 Other Plasma Components .. 12
Table 2 Percentage of Major Proteins Present in Different Fractions After Cohn’s Fractionation Method .. 14
Table 3 Key Trends in Global Blood Plasma .. 17
Table 4 Global Market for Blood Plasma, by Product Type, Through 2021 ($ Millions) .. 23
Table 5 Global Market for Immunoglobulins, by Product Subsegment, Through 2021 ($ Millions) ..24
Table 6 Global Market for Intravenous Immunoglobulins, by Region, Through 2021 ($ Millions) .. 25
Table 7 Global Market for Subcutaneous Immunoglobulins, by Region, Through 2021 ($ Millions) .. 26
Table 8 Global Market for Other Immunoglobulins, by Region, Through 2021 ($ Millions) .. 27
Table 9 Global Market for Immunoglobulins, by Region, Through 2021 ($ Millions) .. 28
Table 10 Global Market for Albumin, by Region, Through 2021 ($ Millions) .. 28
Table 11 Global Market for Hyperimmunes, by Region, Through 2021 ($ Millions) .. 30
Table 12 Global Market for Coagulation Factors, by Region, Through 2021 ($ Millions) .. 31
Table 13 Protease Inhibitors Used in The Treatment of HIV Infection .. 32
Table 14 Global Market for Other Plasma Fractionation Products, by Region, Through 2021 ($ Millions) .. 32
Table 15 Global Market for Blood Plasma Products Used by Hospitals and Clinics, by Region, Through 2021 ($ Millions) .. 35
Table 16 Global Market for Blood Plasma Products Used by Research Institutes, by Region, Through 2021 ($ Millions) .. 36
Table 17 Global Market for Blood Plasma Products Used by Academic Institutions, by Region, Through 2021 ($ Millions) .. 37
Table 18 Global Market for Blood Plasma Products, by Type of End User, Through 2021 ($ Millions) .. 38
Table 19 Global Market for the Application of Blood Plasma Products in Immunology, by Region, Through 2021 ($ Millions) .. 42
Table 20 Global Market for the Application of Blood Plasma Products in Oncology, by Region, Through 2021 ($ Millions) .. 44
Table 21 Global Market for the Application of Blood Plasma Products in Pulmonology, by Region, Through 2021 ($ Millions) .. 45
Table 22 Global Market for the Application of Blood Plasma Products in Rheumatology, by Region, Through 2021 ($ Millions) .. 47
Table 23 Global Market for the Application of Blood Plasma Products in Transplantation, by Region, Through 2021 ($ Millions) .. 48
Table 24 Global Market for the Application of Blood Plasma Products in Neurology, by Region, Through 2021 ($ Millions) .. 51
Table 25 Global Market for the Application of Blood Plasma Products in Hematology, by Region, Through 2021 ($ Millions) .. 52
Table 26 Global Market for the Application of Blood Plasma Products in Other Application Areas, by Region, Through 2021 ($ Millions) .. 52
Table 27 Global Market for Blood Plasma Products, by Area of Medical Application, Through 2021 ($ Millions) .. 53
Table 28 Global Market for Blood Plasma Products, by Region, Through 2021 ($ Millions) .. 61
Table 29 North American Market for Blood Plasma Products, by Country, Through 2021 ($ Millions) .. 62
Table 30 Estimated New Cases of Lymphoma, Leukemia and Myeloma in the U.S., 2017 .. 63
Table 31 North American Market for Blood Plasma Products, by Type, Through 2021 ($ Millions) .. 64
Table 32 North American Market for Immunoglobulin Products, by Type, Through 2021 ($ Millions) ..... 64
Table 33 North American Market for Blood Plasma Products, by Area of Medical Application, Through 2021 ($ Millions) .. 65
Table 34 North American Market for Blood Plasma Products, by End User Type, Through 2021 ($ Millions) .. 65
Table 35 European Market for Blood Plasma Products, by Country/Region, Through 2021 ($ Millions) .. 68
Table 36 Statistical Analysis of Plasma Collection in Europe, 2010–2013 .. 68
Table 37 Statistical Analysis of Plasma Donors in Germany .. 70
Table 38 European Market for Blood Plasma Products, by Type, Through 2021 ($ Millions) .. 71
Table 39 European Market for Immunoglobulin Products by Type, Through 2021 ($ Millions) .. 71
Table 40 European Market for Blood Plasma Products, by Area of Medical Application, Through 2021 ($ Millions) .. 71
Table 41 European Market for Blood Plasma Products, by Type of End User, Through 2021 ($ Millions) .. 72
Table 42 Asia-Pacific Market for Blood Plasma Products, by Country/Region, Through 2021 ($ Millions) .. 76
Table 43 Asia-Pacific Market for Blood Plasma Products, by Type, Through 2021 ($ Millions) .. 76
Table 44 Asia-Pacific Market for Immunoglobulin Products, by Type, Through 2021 ($ Millions) .. 77
Table 45 Asia-Pacific Market for Blood Plasma Products by Area of Medical Application, Through 2021 ($ Millions) .. 77
Table 46 Asia-Pacific Market for Blood Plasma Products by Type of End User, Through 2021 ($ Millions) ..78
Table 47 Statistical Analysis of Plasma Components in China, 2016 (%).. 78
Table 48 RoW Market for Blood Plasma Products, by Co
List of Figures
Summary Figure: Global Market for Blood Plasma, by Region, 2015–2021 ($ Millions) .. 9
Figure 1 Benefits of Blood Donation .. 11
Figure 2 Role of Concentration of Albumin in Maintaining Osmotic Pressure .. 13
Figure 3 Statistical Analysis of Aging Population in the U.S., 2015-2050 .. 19
Figure 4 Segmentation of Global Blood Plasma Market, by Product Type .. 22
Figure 5 Subsegments of the Market for Immunoglobulins .. 24
Figure 6 Categorization of Subcutaneous Immunoglobulins .. 26
Figure 7 Process of Isolation of Hyperimmunes .. 29
Figure 8 Global Segmentation of the Blood Plasma Market, by Type of End User .. 34
Figure 9 Role of Platelet-Rich Plasma in Treatment .. 38
Figure 10 Global Segmentation of Blood Plasma Market, by Area of Medical Application .. 40
Figure 11 Functions of the Immune System .. 41
Figure 12 Conditions Entailing Blood Transfusions .. 43
Figure 13 Symptoms of Lupus Infection .. 46
Figure 14 The Study of Neurology .. 49
Figure 15 Role of Plasma Exchange in the Treatment of Neuroimmunological Disorders .. 50
Figure 16 Categories of Bleeding Disorders .. 51
Figure 17 Frequent Side Effects Associated with Immunoglobulin Infusions .. 55
Figure 18 Rarely Induced Severe Allergic Reactions Associated with Immunoglobulin Infusions .. 56
Figure 19 Procedure for Plasma Gel Treatment .. 57
Figure 20 Role of Fibrin Sealant in Coagulation Cascade .. 58
Figure 21 Distribution of New Cases of Lymphoma, Leukemia and Myeloma in the U.S., 2017 (%) .. 63
Figure 22 U.S. Market for Blood Plasma Products, 2015–2021 ($ Millions) .. 66
Figure 23 Canadian Market for Blood Plasma Products, 2015–2021 ($ Millions) .. 66
Figure 24 Mexican Market for Blood Plasma Products, 2015–2021 ($ Millions) .. 67
Figure 25 Statistical Analysis of Plasma Collection in Europe, 2010–2013 (%) .. 69
Figure 26 Statistical Analysis of Plasma Donors in Germany, 2005–2010 (%) .. 70
Figure 27 U.K. Market for Blood Plasma Products, 2015–2021.. 73
Figure 28 German Market for Blood Plasma Products, 2015–2021 .. 74
Figure 29 French Market for Blood Plasma Products, 2015–2021 .. 74
Figure 30 Rest of European Market for Blood Plasma Products, 2015–2021 ($ Millions) .. 75
Figure 31 Statistical Analysis of Plasma Components in China, 2016 (%).. 79
Figure 32 Chinese Market for Blood Plasma Products, 2015–2021 ($ Millions) .. 79
Figure 33 Japanese Market for Blood Plasma Products, 2015–2021 ($ Millions) .. 80
Figure 34 Australian Market for Blood Plasma Products, 2015–2021 ($ Millions) .. 81
Figure 35 Indian Market for Blood Plasma Products, 2015–2021 ($ Millions) .. 82
Figure 36 Rest of Asia-Pacific Market for Blood Plasma Products, 2015–2021 ($ Millions) .. 83
Figure 37 Latin American Market for Blood Plasma Products, 2015–2021 ($ Millions) .. 86
Figure 38 Statistical Analysis of Ebola Deaths in Africa, 2014–2016 (%).. 87
Figure 39 African Market for Blood Plasma Products, 2015–2021 ($ Millions) .. 87
Figure 40 Middle East Market for Blood Plasma Products, 2015–2021 ($ Millions) .. 88
Figure 41 Distribution of Patents Issued on Blood Plasma Products Annually, 2014–2016 (%).. 91
Figure 42 Global Shares of Patents Issued on Blood Plasma Products, by Region, 2014–2016 (%).. 92
Figure 43 Global Shares of Patents Issued on Blood Plasma Products, by Country, 2014–2016 (%).. 93
Figure 44 Global Shares of Patents on Blood Plasma Products, by Major Company and Other Size Companies, 2014–2016 (%).. 94
Figure 45 Global Shares of Patents Issued for Blood Plasma Products to Other Types of Assignees, 2014–2016 (%).. 95
Figure 46 Distribution of Industry Strategies Used, by Type, 2014-April 2017 (%).. 98
Figure 47 Distribution of “Key” Industry Strategies Used, by Type, 2014-April 2017 (%).. 99
Figure 48 Company Shares of Blood Plasma Product Approvals, 2014-April 2017 (%).. 100
Figure 49 Shares of Expansion Activities, by Company, 2014-April 2017 (No./%) .. 101
Figure 50 Shares of Business Collaborations, by Company, 2014–2017 (%) .. 102
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